一、基本信息

职称：副教授（博士生/硕士生导师）

邮箱：lirui@hainanu.edu.cn

研究兴趣：1. 热带果品采后病害生物防控；2. 果蔬采后生理与分子生物学  

招生专业：作物学博士、园艺学学硕、农艺与种业专硕

二、教育背景

2014-2020 中国农业大学 食品生物技术  博士

2019-2020 加拿大英属哥伦比亚大学  联合培养

2010-2014 郑州轻工业学院 食品质量与安全 学士

三、科研项目

1. 国家自然科学基金青年项目，转录因子MiEIN3在拮抗菌N-1介导的采后芒果炭疽病抗性中的调控机制，2024.01-2026.12，在研，主持

2. 海南省自然科学基金高层次人才项目，拮抗菌介导的采后芒果炭疽病抗性中EIN3的功能及作用机制研究，2024.01-2026.12，在研，主持

3. 海南省自然科学基金青年基金项目，HuNPR1参与调控拮抗菌N-1介导的采后火龙果果实软腐病抗性的分子机制，2021.03-2024.03，在研，主持

4. 海南大学科研启动基金项目，NPR1参与调控拮抗菌介导的热带果品采后抗病性的分子机制，2021.03-2026.03，在研，主持

5.海南大学青年教师科研培育项目，MiEIN3在拮抗菌N-1介导的采后芒果抗病性中的作用机制，2023.04-2023.11，已结题，主持

6.国家自然科学基金面上项目，细胞自噬参与NO诱导番茄果实抗灰霉病作用机制研究，2021.01-2024.12，在研，参加

7. 国家自然科学基金面上项目，NO 诱导采后番茄果实抗病中NPR1 与MAPK 的协同互作机制研究，2014.01-2016.12，已结题，参加

8.国家自然科学基金面上项目，项目编号32072275，MYB和ERF转录因子协同调控采后“贵妃”芒果花青素代谢的机制研究，2021.01-2024.01, 参加

四、代表性成果

1. Rui Li; Yujing Li; Yuelin Zhang; Jiping Sheng; Hongliang Zhu; Lin Shen*; Transcriptome analysis reveals that SlNPR1 mediates tomato fruit resistance against Botrytis cinerea by modulating phenylpropanoid metabolism and balancing ROS homeostasis, Postharvest Biology and Technology, 2021, 172.  

2. Rui Li; Lixing Zhang; Liu Wang; Lin Chen; Ruirui Zhao; Jiping Sheng; Lin Shen*; Reduction of Tomato-Plant Chilling Tolerance by CRISPR–Cas9-Mediated SlCBF1 Mutagenesis, Journal of Agricultural and Food Chemistry, 2018, 66(34): 9042-9051.  

3. Rui Li; Chunxue Liu; Ruirui Zhao; Liu Wang; Lin Chen; Wenqing Yu; Shujuan Zhang; Jiping Sheng; Lin Shen*; CRISPR/Cas9-Mediated SlNPR1 mutagenesis reduces tomato plant drought tolerance, BMC Plant Biology, 2019, 19: 38.  

4. Rui Li; Liu Wang; Yujing Li; Ruirui Zhao; Yuelin Zhang; Jiping Sheng; Peihua Ma; Lin Shen*; Knockout of SlNPR1 enhances tomato plants resistance against Botrytis cinerea by modulating ROS homeostasis and JA/ET signaling pathways, Physiologia Plantarum, 2020, 170(4): 569-579.    

5. Rui Li; Jiping Sheng; Lin Shen*; Nitric Oxide Plays an Important Role in β-Aminobutyric Acid-Induced Resistance to Botrytis cinerea in Tomato Plants, Plant Pathology Journal, 2020, 36(2): 121-132.  

6. Jian Xu; Yaru Zheng; Dengfan Peng; Yuanzhi Shao; Rui Li*; Wen Li*; Bacillus siamensis N-1 improves fruit quality and disease resistance by regulating ROS homeostasis and defense enzyme activities in pitaya, Scientia Horticulturae, 2024, 329:112975.

7. Rui Li^#, Jiheng Ma^#, Hui Gu, Wenjun Jia, Yuanzhi Shao*, Wen Li*, 1-methylcyclopropene counteracts ethylene promotion of fruit softening and roles of MiERF2/8 and MiPG in postharvest mangoes, 2022, Frontiers in Plant Science, 13:971050.

8. Mingmin Chen, Hui Gu, Lirong Wang, Yuanzhi Shao, Rui Li*, Wen Li*; Exogenous ethylene promotes peel color transformation by regulating the degradation of chlorophyll and synthesis of anthocyanin in postharvest mango fruit, 2022, Frontiers in Nutrition, 9: 911542.

9. Zecheng Jiang, Rui Li, Yue Tang, Ziyu Cheng, Minjie Qian, Wen Li*, Yuanzhi Shao*; Transcriptome Analysis Reveals the Inducing Effect of Bacillus siamensis on Disease Resistance in Postharvest Mango Fruit, 2022, Foods, 11(1):107.

10. Nan Wang, Yuwei Nian, Rui Li, Yuanzhi Shao*, Wen Li*; Transcription Factor CpbHLH3 and CpXYN1 Gene Cooperatively Regulate Fruit Texture and Counteract 1-Methylcyclopropene Inhibition of Softening in Postharvest Papaya (Carica papaya L.), 2022, Journal of Agricultural and Food Chemistry, 70(32).

11. Yue Tang, Rui Li, Zecheng Jiang, Zi-Qian Cheng, Wen Li*, Y. Shao*; Combined effect of Debaryomyces hansenii and Bacillus atrophaeus on the physicochemical attributes, defense-related enzyme activity, and transcriptomic profile of stored litchi fruit, Biological Control, 2022, 172(2–3):104975.

12. Ziyu Cheng, Rui Li, Zecheng Jiang, Yue Tang, Wen Li*, Y. Shao*; Combined effect of Bacillus siamensis and chlorogenic acid on maintenance of quality, control of disease in stored wax apple fruit, 2022, Food Quality and Safety 6(3).

13. Lin Chen, Xue Zhao, Rui Li, Hongshun Yang*; Integrated metabolomics and transcriptomics reveal the adaptive responses of Salmonella enterica serovar Typhimurium to thyme and cinnamon oils, 2022, Food Research International, 157:111241.

14. Yuwei Nian, NanWang, Rui Li, Yuanzhi Shao*, WenLi*; Cold shock treatment alleviates chilling injury in papaya fruit during storage by improving antioxidant capacity and related gene expression, 2022, Scientia Horticulturae 294(6):110784.

15. Chunhui Ge, Wenjing You, Rui Li, Wen Li*, Yuanzhi Shao*; Construction of the PG-deficient mutant of Fusarium equiseti by CRISPR/Cas9 and its pathogenicity of pitaya, 2021, Journal of Basic Microbiology, 61(8), 686-696.

16. Chunxue Liu, Lingling Chen, Ruirui Zhao, Rui Li, Shujuan Zhang, Wenqing Yu, Jiping Sheng, Lin Shen*; Melatonin Induces Disease Resistance to Botrytis cinerea in Tomato Fruit by Activating Jasmonic Acid Signaling Pathway, Journal of Agricultural and Food Chemistry, 2019. 67(22):6116-6124.

17. Liu Wang, Ruirui Zhao, Rui Li, Wenqing Yu, Meijing Yang, Jiping Sheng, Lin Shen*; Enhanced drought tolerance in tomato plants by overexpression of SlMAPK1, Plant Cell, Tissue and Organ Culture, 2018. 133, 27–38.

18. Liu Wang, Lin Chen, Rui Li, Ruirui Zhao, Meijing Yang, Jiping Sheng, and Lin Shen*; Reduced drought tolerance by CRISPR/Cas9-mediated SlMAPK3 mutagenesis in tomato plants, Journal of Agricultural and Food Chemistry, 2017.  65, 39, 8674–8682.

19. Tian Wang, Rui Li, Liwei Wen, Daqi Fu, Benzhong Zhu, Yunbo Luo, Hongliang Zhu*; Functional analysis and RNA sequencing indicate the regulatory role of argonaute1 in tomato compound leaf development, PLoS One. 2015,10(10), e0140756.